Erlotinib D6 HCl
- Product Name
- Erlotinib D6 HCl
- CAS No.
- 1189953-78-3
- Chemical Name
- Erlotinib D6 HCl
- Synonyms
- Erlotinib D6;OSI-774 D6 hydrochloride;Erlotiniβ-d6 Hydrochloride;CP-358774 D6 hydrochloride;NSC 718781 D6 hydrochloride;[2H6]-Erlotinib Hydrochloride;Erlotinib Hydrochloride Impurity G
- CBNumber
- CB03049808
- Molecular Formula
- C22H18ClD6N3O4
- Formula Weight
- 435.933630668
- MOL File
- 1189953-78-3.mol
Erlotinib D6 HCl Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: slightly, heated,Methanol: slightly soluble
- form
- A solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 22101
- Product name
- Erlotinib-d6 (hydrochloride)
- Purity
- ≥99% deuterated forms (d1-d6)
- Packaging
- 1mg
- Price
- $279
- Updated
- 2024/03/01
- Product number
- E625002
- Product name
- Erlotinib-d6Hydrochloride
- Packaging
- 1mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- 7728DG
- Product name
- ErlotinibD6Hydrochloride
- Packaging
- 1mg
- Price
- $409
- Updated
- 2021/12/16
- Product number
- RDL0006809
- Product name
- ERLOTINIB-D6-HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $1871.1
- Updated
- 2021/12/16
Erlotinib D6 HCl Chemical Properties,Usage,Production
Description
Erlotinib-d6 (hydrochloride) contains six deuterium atoms located on the methoxy group. It is intended for use as an internal standard for the quantification of erlotinib by GC- or LC-MS. Erlotinib is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity (IC50 = 2.5 μM). This inhibits tumor growth in human head and neck carcinoma (HN5) tumor xenografts in mice with an ED50 value of 9 mg/kg. Erlotinib also suppresses cyclin-dependent kinase 2 (Cdk2) activity in breast cancer cells (IC50 = 4.6 μM) and JAK2 mutant JAK2V617F (IC50 = 5 μM), which is associated with polycythemia vera, idiopathic myelofibrosis, and essential thrombocythemia. Formulations containing erlotinib are used to treat certain forms of cancer, including non-small cell lung cancer.
Uses
Erlotinib D6 HCl is a Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor, Antineoplastic.;Labeled Erlotinib, intended for use as an internal standard for the quantification of Erlotinib by GC- or LC-mass spectrometry.
Erlotinib D6 HCl Preparation Products And Raw materials
Raw materials
Preparation Products
Erlotinib D6 HCl Suppliers
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